Temporary Treatment during Primary HIV Infection Does Not Affect Virologic Response to Subsequent Long-Term Treatment

Temporary cART during primary HIV-infection (PHI) did not select for drug resistance mutations after treatment interruption and did not affect the subsequent virological response to long-term cART. Our data demonstrate that fear of drug resistance development is not a valid argument to refrain from...

Descripción completa

Detalles Bibliográficos
Autores principales: Grijsen, Marlous L., Wit, Ferdinand W. N. M., Jurriaans, Suzanne, Kroon, Frank P., Schippers, Emile F., Koopmans, Peter, Gras, Luuk, Lange, Joep M. A., Prins, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974663/
https://www.ncbi.nlm.nih.gov/pubmed/24699072
http://dx.doi.org/10.1371/journal.pone.0089639
Descripción
Sumario:Temporary cART during primary HIV-infection (PHI) did not select for drug resistance mutations after treatment interruption and did not affect the subsequent virological response to long-term cART. Our data demonstrate that fear of drug resistance development is not a valid argument to refrain from temporary early treatment during PHI.

Ejemplares similares