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Expansion of Parasite-Specific CD4(+) and CD8(+) T Cells Expressing IL-10 Superfamily Cytokine Members and Their Regulation in Human Lymphatic Filariasis
BACKGROUND: Lymphatic filariasis (LF) is known to be associated with an increased production of IL-10. The role of the other IL-10 family members in the pathogenesis of infection and/or disease is not known. METHODOLOGY/PRINCIPAL FINDINGS: We examined the expression patterns of IL-10 family members...
Autores principales: | Anuradha, Rajamanickam, George, Parakkal Jovvian, Hanna, Luke E., Kumaran, Paul, Chandrasekaran, Vedachalam, Nutman, Thomas B., Babu, Subash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974669/ https://www.ncbi.nlm.nih.gov/pubmed/24699268 http://dx.doi.org/10.1371/journal.pntd.0002762 |
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