High Fidelity Copy Number Analysis of Formalin-Fixed and Paraffin-Embedded Tissues Using Affymetrix Cytoscan HD Chip

Detection of human genome copy number variation (CNV) is one of the most important analyses in diagnosing human malignancies. Genome CNV detection in formalin-fixed and paraffin-embedded (FFPE) tissues remains challenging due to suboptimal DNA quality and failure to use appropriate baseline controls...

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Detalles Bibliográficos
Autores principales: Yu, Yan P., Michalopoulos, Amantha, Ding, Ying, Tseng, George, Luo, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974686/
https://www.ncbi.nlm.nih.gov/pubmed/24699316
http://dx.doi.org/10.1371/journal.pone.0092820

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