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The pleiotropic effects of the hydroxy-methyl-glutaryl-CoA reductase inhibitors in renal disease

It is well known that statins exert their main effect by inhibiting cholesterol synthesis through the inhibition of the 3-hydroxy-3-methyl-glutaryl-CoA reductase enzyme. The pleiotropic effects of statins, which are independent of their inhibition of cholesterol synthesis, have explained many of the...

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Detalles Bibliográficos
Autores principales:	Gomez, Sabas I, Mihos, Christos G, Pineda, Andres M, Santana, Orlando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974687/ https://www.ncbi.nlm.nih.gov/pubmed/24729724 http://dx.doi.org/10.2147/IJNRD.S55102

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