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Spink2 Modulates Apoptotic Susceptibility and Is a Candidate Gene in the Rgcs1 QTL That Affects Retinal Ganglion Cell Death after Optic Nerve Damage

The Rgcs1 quantitative trait locus, on mouse chromosome 5, influences susceptibility of retinal ganglion cells to acute damage of the optic nerve. Normally resistant mice (DBA/2J) congenic for the susceptible allele from BALB/cByJ mice exhibit susceptibility to ganglion cells, not only in acute opti...

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Detalles Bibliográficos
Autores principales: Dietz, Joel A., Maes, Margaret E., Huang, Shuang, Yandell, Brian S., Schlamp, Cassandra L., Montgomery, Angela D., Allingham, R. Rand, Hauser, Michael A., Nickells, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974755/
https://www.ncbi.nlm.nih.gov/pubmed/24699552
http://dx.doi.org/10.1371/journal.pone.0093564