Regulation of Human T-Lymphotropic Virus Type I Latency and Reactivation by HBZ and Rex

Human T lymphotropic virus type I (HTLV-I) infection is largely latent in infected persons. How HTLV-1 establishes latency and reactivates is unclear. Here we show that most HTLV-1-infected HeLa cells become senescent. By contrast, when NF-κB activity is blocked, senescence is averted, and infected...

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Detalles Bibliográficos
Autores principales: Philip, Subha, Zahoor, Muhammad Atif, Zhi, Huijun, Ho, Yik-Khuan, Giam, Chou-Zen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974842/
https://www.ncbi.nlm.nih.gov/pubmed/24699669
http://dx.doi.org/10.1371/journal.ppat.1004040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974842/
https://www.ncbi.nlm.nih.gov/pubmed/24699669
http://dx.doi.org/10.1371/journal.ppat.1004040

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