Inactivation of Genes for Antigenic Variation in the Relapsing Fever Spirochete Borrelia hermsii Reduces Infectivity in Mice and Transmission by Ticks

Borrelia hermsii, a causative agent of relapsing fever of humans in western North America, is maintained in enzootic cycles that include small mammals and the tick vector Ornithodoros hermsi. In mammals, the spirochetes repeatedly evade the host’s acquired immune response by undergoing antigenic var...

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Detalles Bibliográficos
Autores principales: Raffel, Sandra J., Battisti, James M., Fischer, Robert J., Schwan, Tom G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974855/
https://www.ncbi.nlm.nih.gov/pubmed/24699793
http://dx.doi.org/10.1371/journal.ppat.1004056

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