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The caspase-3 inhibitor (peptide Z-DEVD-FMK) affects the survival and function of platelets in platelet concentrate during storage

BACKGROUND: Although apoptosis occurs in nucleated cells, studies show that this event also occurs in some anucleated cells such as platelets. During storage of platelets, the viability of platelets decreased, storage lesions were observed, and cells underwent apoptosis. We investigated the effects...

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Detalles Bibliográficos
Autores principales: Shiri, Reza, Yari, Fatemeh, Ahmadinejad, Minoo, Vaeli, Shahram, Tabatabaei, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974957/
https://www.ncbi.nlm.nih.gov/pubmed/24724067
http://dx.doi.org/10.5045/br.2014.49.1.49