Genome-Wide Analysis of DNA Methylation, Copy Number Variation, and Gene Expression in Monozygotic Twins Discordant for Primary Biliary Cirrhosis

Primary biliary cirrhosis (PBC) is an uncommon autoimmune disease with a homogeneous clinical phenotype that reflects incomplete disease concordance in monozygotic (MZ) twins. We have taken advantage of a unique collection consisting of genomic DNA and mRNA from peripheral blood cells of female MZ t...

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Detalles Bibliográficos
Autores principales: Selmi, Carlo, Cavaciocchi, Francesca, Lleo, Ana, Cheroni, Cristina, De Francesco, Raffaele, Lombardi, Simone A., De Santis, Maria, Meda, Francesca, Raimondo, Maria Gabriella, Crotti, Chiara, Folci, Marco, Zammataro, Luca, Mayo, Marlyn J., Bach, Nancy, Shimoda, Shinji, Gordon, Stuart C., Miozzo, Monica, Invernizzi, Pietro, Podda, Mauro, Scavelli, Rossana, Martin, Michelle R., Seldin, Michael F., LaSalle, Janine M., Gershwin, M. Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975093/
https://www.ncbi.nlm.nih.gov/pubmed/24734033
http://dx.doi.org/10.3389/fimmu.2014.00128

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