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Functional polymorphism in aldehyde dehydrogenase-2 gene associated with risk of tuberculosis
BACKGROUND: The well-known genetic polymorphisms in ADH1B(His47Arg) and ALDH2(Glu487Lys) have dramatic effects on the rate of metabolizing alcohol and acetaldehyde. We investigated possible involvement of these functional polymorphisms in other common complex-trait diseases. METHODS: The genetic eff...
Autores principales: | Park, Seung Kyu, Park, Choon-Sik, Lee, Hyo-Suk, Park, Kyong Soo, Park, Byung Lae, Cheong, Hyun Sub, Shin, Hyoung Doo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975138/ https://www.ncbi.nlm.nih.gov/pubmed/24690209 http://dx.doi.org/10.1186/1471-2350-15-40 |
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