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Contributions of epithelial-mesenchymal transition and cancer stem cells to the development of castration resistance of prostate cancer
An important clinical challenge in prostate cancer therapy is the inevitable transition from androgen-sensitive to castration-resistant and metastatic prostate cancer. Albeit the androgen receptor (AR) signaling axis has been targeted, the biological mechanism underlying the lethal event of androgen...
Autores principales: | Li, Ping, Yang, Ru, Gao, Wei-Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975176/ https://www.ncbi.nlm.nih.gov/pubmed/24618337 http://dx.doi.org/10.1186/1476-4598-13-55 |
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