Certolizumab-Induced Uveitis: A Case Report and Review of the Literature

We report the case of a 64-year-old woman with rheumatoid arthritis and bilateral visual deterioration. The patient had been treated with certolizumab, a new tumor necrosis factor alpha (TNFα) antagonist, and her findings were consistent with bilateral uveitis, suggestive of sarcoidosis. Here, we re...

Descripción completa

Detalles Bibliográficos
Autores principales: Moisseiev, Elad, Shulman, Shiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Published online: February, 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975203/
https://www.ncbi.nlm.nih.gov/pubmed/24707273
http://dx.doi.org/10.1159/000358324
_version_ 1782310103757619200
author Moisseiev, Elad
Shulman, Shiri
author_facet Moisseiev, Elad
Shulman, Shiri
author_sort Moisseiev, Elad
collection PubMed
description We report the case of a 64-year-old woman with rheumatoid arthritis and bilateral visual deterioration. The patient had been treated with certolizumab, a new tumor necrosis factor alpha (TNFα) antagonist, and her findings were consistent with bilateral uveitis, suggestive of sarcoidosis. Here, we review the literature on TNFα antagonist-induced sarcoidosis and report the first case of uveitis induced by certolizumab. Awareness of the possibility of this unique complication is important for both rheumatologists and ophthalmologists who treat patients with this new agent.
format Online
Article
Text
id pubmed-3975203
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher S. Karger AG
record_format MEDLINE/PubMed
spelling pubmed-39752032014-04-04 Certolizumab-Induced Uveitis: A Case Report and Review of the Literature Moisseiev, Elad Shulman, Shiri Case Rep Ophthalmol Published online: February, 2014 We report the case of a 64-year-old woman with rheumatoid arthritis and bilateral visual deterioration. The patient had been treated with certolizumab, a new tumor necrosis factor alpha (TNFα) antagonist, and her findings were consistent with bilateral uveitis, suggestive of sarcoidosis. Here, we review the literature on TNFα antagonist-induced sarcoidosis and report the first case of uveitis induced by certolizumab. Awareness of the possibility of this unique complication is important for both rheumatologists and ophthalmologists who treat patients with this new agent. S. Karger AG 2014-02-12 /pmc/articles/PMC3975203/ /pubmed/24707273 http://dx.doi.org/10.1159/000358324 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: February, 2014
Moisseiev, Elad
Shulman, Shiri
Certolizumab-Induced Uveitis: A Case Report and Review of the Literature
title Certolizumab-Induced Uveitis: A Case Report and Review of the Literature
title_full Certolizumab-Induced Uveitis: A Case Report and Review of the Literature
title_fullStr Certolizumab-Induced Uveitis: A Case Report and Review of the Literature
title_full_unstemmed Certolizumab-Induced Uveitis: A Case Report and Review of the Literature
title_short Certolizumab-Induced Uveitis: A Case Report and Review of the Literature
title_sort certolizumab-induced uveitis: a case report and review of the literature
topic Published online: February, 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975203/
https://www.ncbi.nlm.nih.gov/pubmed/24707273
http://dx.doi.org/10.1159/000358324
work_keys_str_mv AT moisseievelad certolizumabinduceduveitisacasereportandreviewoftheliterature
AT shulmanshiri certolizumabinduceduveitisacasereportandreviewoftheliterature

Ejemplares similares