Cargando…
Perforated Sigmoid Diverticulitis in the Presence of Toxic Epidermal Necrolysis
Even though the incidence of toxic epidermal necrolysis (TEN) is low, it is also associated with a high mortality rate. The condition predominantly affects the skin, but may also affect the gastrointestinal tract, dramatically increasing mortality. We present a case of perforated sigmoid diverticuli...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975207/ https://www.ncbi.nlm.nih.gov/pubmed/24707250 http://dx.doi.org/10.1159/000360129 |
_version_ | 1782310104723357696 |
---|---|
author | Heye, P. Descloux, A. Singer, G. Rosenberg, R. Kocher, T. |
author_facet | Heye, P. Descloux, A. Singer, G. Rosenberg, R. Kocher, T. |
author_sort | Heye, P. |
collection | PubMed |
description | Even though the incidence of toxic epidermal necrolysis (TEN) is low, it is also associated with a high mortality rate. The condition predominantly affects the skin, but may also affect the gastrointestinal tract, dramatically increasing mortality. We present a case of perforated sigmoid diverticulitis in the presence of TEN. The patient was taking medication, known to be a risk factor, and presented an affected total body surface area and temporal development similar to previously reported cases of TEN. Characteristic abdominal symptoms, however, were missing. Gastrointestinal involvement in TEN appears to be a poor prognostic factor; medical staff must therefore be alert to patients with TEN who complain of abdominal discomfort. The exact pathogenesis, however, remains unclear. |
format | Online Article Text |
id | pubmed-3975207 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-39752072014-04-04 Perforated Sigmoid Diverticulitis in the Presence of Toxic Epidermal Necrolysis Heye, P. Descloux, A. Singer, G. Rosenberg, R. Kocher, T. Case Rep Dermatol Published online: February, 2014 Even though the incidence of toxic epidermal necrolysis (TEN) is low, it is also associated with a high mortality rate. The condition predominantly affects the skin, but may also affect the gastrointestinal tract, dramatically increasing mortality. We present a case of perforated sigmoid diverticulitis in the presence of TEN. The patient was taking medication, known to be a risk factor, and presented an affected total body surface area and temporal development similar to previously reported cases of TEN. Characteristic abdominal symptoms, however, were missing. Gastrointestinal involvement in TEN appears to be a poor prognostic factor; medical staff must therefore be alert to patients with TEN who complain of abdominal discomfort. The exact pathogenesis, however, remains unclear. S. Karger AG 2014-02-15 /pmc/articles/PMC3975207/ /pubmed/24707250 http://dx.doi.org/10.1159/000360129 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published online: February, 2014 Heye, P. Descloux, A. Singer, G. Rosenberg, R. Kocher, T. Perforated Sigmoid Diverticulitis in the Presence of Toxic Epidermal Necrolysis |
title | Perforated Sigmoid Diverticulitis in the Presence of Toxic Epidermal Necrolysis |
title_full | Perforated Sigmoid Diverticulitis in the Presence of Toxic Epidermal Necrolysis |
title_fullStr | Perforated Sigmoid Diverticulitis in the Presence of Toxic Epidermal Necrolysis |
title_full_unstemmed | Perforated Sigmoid Diverticulitis in the Presence of Toxic Epidermal Necrolysis |
title_short | Perforated Sigmoid Diverticulitis in the Presence of Toxic Epidermal Necrolysis |
title_sort | perforated sigmoid diverticulitis in the presence of toxic epidermal necrolysis |
topic | Published online: February, 2014 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975207/ https://www.ncbi.nlm.nih.gov/pubmed/24707250 http://dx.doi.org/10.1159/000360129 |
work_keys_str_mv | AT heyep perforatedsigmoiddiverticulitisinthepresenceoftoxicepidermalnecrolysis AT desclouxa perforatedsigmoiddiverticulitisinthepresenceoftoxicepidermalnecrolysis AT singerg perforatedsigmoiddiverticulitisinthepresenceoftoxicepidermalnecrolysis AT rosenbergr perforatedsigmoiddiverticulitisinthepresenceoftoxicepidermalnecrolysis AT kochert perforatedsigmoiddiverticulitisinthepresenceoftoxicepidermalnecrolysis |