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Zoledronic acid inhibits pulmonary metastasis dissemination in a preclinical model of Ewing’s sarcoma via inhibition of cell migration

BACKGROUND: Ewing’s sarcoma (ES) is the second most frequent primitive malignant bone tumor in adolescents with a very poor prognosis for high risk patients, mainly when lung metastases are detected (overall survival <15% at 5 years). Zoledronic acid (ZA) is a potent inhibitor of bone resorption...

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Detalles Bibliográficos
Autores principales: Odri, Guillaume, Kim, Pui-Pui, Lamoureux, François, Charrier, Céline, Battaglia, Séverine, Amiaud, Jérôme, Heymann, Dominique, Gouin, François, Redini, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975287/
https://www.ncbi.nlm.nih.gov/pubmed/24612486
http://dx.doi.org/10.1186/1471-2407-14-169

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