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Novel Missense Mutation in the NOD2 Gene in a Patient with Early Onset Ulcerative Colitis: Causal or Chance Association?

Deregulated immune response to gut microflora in genetically predisposed individuals is typical for inflammatory bowel diseases. It is reasonable to assume that genetic association with the disease will be more pronounced in subjects with early onset than adult onset. The nucleotide-binding oligomer...

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Detalles Bibliográficos
Autores principales: Girardelli, Martina, Vuch, Josef, Tommasini, Alberto, Crovella, Sergio, Bianco, Anna Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975370/
https://www.ncbi.nlm.nih.gov/pubmed/24595243
http://dx.doi.org/10.3390/ijms15033834