Intratumoral Decorin Gene Delivery by AAV Vector Inhibits Brain Glioblastomas and Prolongs Survival of Animals by Inducing Cell Differentiation

Glioblastoma multiforme (GBM) is the most malignant cancer in the central nervous system with poor clinical prognosis. In this study, we investigated the therapeutic effect of an anti-cancer protein, decorin, by delivering it into a xenograft U87MG glioma tumor in the brain of nude mice through an a...

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Detalles Bibliográficos
Autores principales: Ma, Hsin-I, Hueng, Dueng-Yuan, Shui, Hao-Ai, Han, Jun-Ming, Wang, Chi-Hsien, Lai, Ying-Hsiu, Cheng, Shi-Yuan, Xiao, Xiao, Chen, Ming-Teh, Yang, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975403/
https://www.ncbi.nlm.nih.gov/pubmed/24625664
http://dx.doi.org/10.3390/ijms15034393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975403/
https://www.ncbi.nlm.nih.gov/pubmed/24625664
http://dx.doi.org/10.3390/ijms15034393

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