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Intratumoral Decorin Gene Delivery by AAV Vector Inhibits Brain Glioblastomas and Prolongs Survival of Animals by Inducing Cell Differentiation
Glioblastoma multiforme (GBM) is the most malignant cancer in the central nervous system with poor clinical prognosis. In this study, we investigated the therapeutic effect of an anti-cancer protein, decorin, by delivering it into a xenograft U87MG glioma tumor in the brain of nude mice through an a...
Autores principales: | Ma, Hsin-I, Hueng, Dueng-Yuan, Shui, Hao-Ai, Han, Jun-Ming, Wang, Chi-Hsien, Lai, Ying-Hsiu, Cheng, Shi-Yuan, Xiao, Xiao, Chen, Ming-Teh, Yang, Yi-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975403/ https://www.ncbi.nlm.nih.gov/pubmed/24625664 http://dx.doi.org/10.3390/ijms15034393 |
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