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Optimization of AAV expression cassettes to improve packaging capacity and transgene expression in neurons

Adeno-associated virus (AAV) vectors can deliver transgenes to diverse cell types and are therefore useful for basic research and gene therapy. Although AAV has many advantages over other viral vectors, its relatively small packaging capacity limits its use for delivering large genes. The available...

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Detalles Bibliográficos
Autores principales:	Choi, Jun-Hyeok, Yu, Nam-Kyung, Baek, Gi-Chul, Bakes, Joseph, Seo, Daekwan, Nam, Hye Jin, Baek, Sung Hee, Lim, Chae-Seok, Lee, Yong-Seok, Kaang, Bong-Kiun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975461/ https://www.ncbi.nlm.nih.gov/pubmed/24618276 http://dx.doi.org/10.1186/1756-6606-7-17

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