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Isoflurane reduces hypoxia/reoxygenation-induced apoptosis and mitochondrial permeability transition in rat primary cultured cardiocytes

BACKGROUND: The volatile anesthetic isoflurane protects the heart from hypoxia/reperfusion (H/R) injury. However, it is still incompletely understood whether isoflurane exerts its protective role through preventing mitochondrial permeability transition pore (MPTP) opening. METHODS: Primary cultured...

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Detalles Bibliográficos
Autores principales: Wu, Wanjun, Zhou, Xianju, Liu, Ping, Fei, Weidong, Li, Li, Yun, Huifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975578/
https://www.ncbi.nlm.nih.gov/pubmed/24612850
http://dx.doi.org/10.1186/1471-2253-14-17