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Hemodialysis without Anticoagulation for a Patient with Chronic Disseminated Intravascular Coagulation

We report a 68-year-old Japanese man with end-stage renal failure requiring hemodialysis and chronic disseminated intravascular coagulation (DIC) related to thrombosis in an aortic aneurysm. He had undergone graft replacement for the dissection of the ascending and descending thoracic aorta in 1990...

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Autores principales: Yamanouchi, Masayuki, Ubara, Yoshifumi, Mise, Koki, Hayami, Noriko, Hiramatsu, Rikako, Sumida, Keiichi, Suwabe, Tatsuya, Hasegawa, Eiko, Hoshino, Junichi, Sawa, Naoki, Takemoto, Fumi, Takaichi, Kenmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975721/
https://www.ncbi.nlm.nih.gov/pubmed/24707280
http://dx.doi.org/10.1159/000358269
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author Yamanouchi, Masayuki
Ubara, Yoshifumi
Mise, Koki
Hayami, Noriko
Hiramatsu, Rikako
Sumida, Keiichi
Suwabe, Tatsuya
Hasegawa, Eiko
Hoshino, Junichi
Sawa, Naoki
Takemoto, Fumi
Takaichi, Kenmei
author_facet Yamanouchi, Masayuki
Ubara, Yoshifumi
Mise, Koki
Hayami, Noriko
Hiramatsu, Rikako
Sumida, Keiichi
Suwabe, Tatsuya
Hasegawa, Eiko
Hoshino, Junichi
Sawa, Naoki
Takemoto, Fumi
Takaichi, Kenmei
author_sort Yamanouchi, Masayuki
collection PubMed
description We report a 68-year-old Japanese man with end-stage renal failure requiring hemodialysis and chronic disseminated intravascular coagulation (DIC) related to thrombosis in an aortic aneurysm. He had undergone graft replacement for the dissection of the ascending and descending thoracic aorta in 1990 and 2002, respectively. Computed tomography disclosed an aneurysm with thrombosis in the residual aorta adjacent to the graft anastomosis. DIC was diagnosed based on elevation of serum fibrinogen degradation products while his activated partial thromboplastin time, prothrombin time and fibrinogen level were normal. In 2008, hemodialysis was initiated for end-stage renal failure. Dialysis was performed without administration of an anticoagulant because his activated clotting time (ACT) was prolonged to 150–180 s. Thereafter, stable hemodialysis continued without clotting in the dialysis circuit until 2013. If monitoring of ACT can be done, hemodialysis without anticoagulation may be a therapeutic option in such patients.
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spelling pubmed-39757212014-04-04 Hemodialysis without Anticoagulation for a Patient with Chronic Disseminated Intravascular Coagulation Yamanouchi, Masayuki Ubara, Yoshifumi Mise, Koki Hayami, Noriko Hiramatsu, Rikako Sumida, Keiichi Suwabe, Tatsuya Hasegawa, Eiko Hoshino, Junichi Sawa, Naoki Takemoto, Fumi Takaichi, Kenmei Case Rep Nephrol Urol Published online: February, 2014 We report a 68-year-old Japanese man with end-stage renal failure requiring hemodialysis and chronic disseminated intravascular coagulation (DIC) related to thrombosis in an aortic aneurysm. He had undergone graft replacement for the dissection of the ascending and descending thoracic aorta in 1990 and 2002, respectively. Computed tomography disclosed an aneurysm with thrombosis in the residual aorta adjacent to the graft anastomosis. DIC was diagnosed based on elevation of serum fibrinogen degradation products while his activated partial thromboplastin time, prothrombin time and fibrinogen level were normal. In 2008, hemodialysis was initiated for end-stage renal failure. Dialysis was performed without administration of an anticoagulant because his activated clotting time (ACT) was prolonged to 150–180 s. Thereafter, stable hemodialysis continued without clotting in the dialysis circuit until 2013. If monitoring of ACT can be done, hemodialysis without anticoagulation may be a therapeutic option in such patients. S. Karger AG 2014-02-18 /pmc/articles/PMC3975721/ /pubmed/24707280 http://dx.doi.org/10.1159/000358269 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: February, 2014
Yamanouchi, Masayuki
Ubara, Yoshifumi
Mise, Koki
Hayami, Noriko
Hiramatsu, Rikako
Sumida, Keiichi
Suwabe, Tatsuya
Hasegawa, Eiko
Hoshino, Junichi
Sawa, Naoki
Takemoto, Fumi
Takaichi, Kenmei
Hemodialysis without Anticoagulation for a Patient with Chronic Disseminated Intravascular Coagulation
title Hemodialysis without Anticoagulation for a Patient with Chronic Disseminated Intravascular Coagulation
title_full Hemodialysis without Anticoagulation for a Patient with Chronic Disseminated Intravascular Coagulation
title_fullStr Hemodialysis without Anticoagulation for a Patient with Chronic Disseminated Intravascular Coagulation
title_full_unstemmed Hemodialysis without Anticoagulation for a Patient with Chronic Disseminated Intravascular Coagulation
title_short Hemodialysis without Anticoagulation for a Patient with Chronic Disseminated Intravascular Coagulation
title_sort hemodialysis without anticoagulation for a patient with chronic disseminated intravascular coagulation
topic Published online: February, 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975721/
https://www.ncbi.nlm.nih.gov/pubmed/24707280
http://dx.doi.org/10.1159/000358269
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