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Inhibition of mammalian target of rapamycin improves neurobehavioral deficit and modulates immune response after intracerebral hemorrhage in rat

BACKGROUND: Mammalian target of rapamycin (mTOR), a serine/threonine kinase, regulates many processes, including cell growth and the immune response. mTOR is also dysregulated in several neurological diseases, such as traumatic brain injury (TBI), stroke, and neurodegenerative disease. However, the...

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Detalles Bibliográficos
Autores principales: Lu, Qin, Gao, Lu, Huang, Lijie, Ruan, Linhui, Yang, Jianjing, Huang, Weilong, Li, Zhenxing, Zhang, Yongliang, Jin, Kunlin, Zhuge, Qichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975837/
https://www.ncbi.nlm.nih.gov/pubmed/24602288
http://dx.doi.org/10.1186/1742-2094-11-44