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Inhibition of mammalian target of rapamycin improves neurobehavioral deficit and modulates immune response after intracerebral hemorrhage in rat
BACKGROUND: Mammalian target of rapamycin (mTOR), a serine/threonine kinase, regulates many processes, including cell growth and the immune response. mTOR is also dysregulated in several neurological diseases, such as traumatic brain injury (TBI), stroke, and neurodegenerative disease. However, the...
Autores principales: | Lu, Qin, Gao, Lu, Huang, Lijie, Ruan, Linhui, Yang, Jianjing, Huang, Weilong, Li, Zhenxing, Zhang, Yongliang, Jin, Kunlin, Zhuge, Qichuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975837/ https://www.ncbi.nlm.nih.gov/pubmed/24602288 http://dx.doi.org/10.1186/1742-2094-11-44 |
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