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5-methoxyindole metabolites of L-tryptophan: control of COX-2 expression, inflammation and tumorigenesis
Cyclooxygenase-2(COX-2) overexpression promotes inflammation and tumorigenesis. COX-2 expression in response to diverse stimuli is tightly controlled to avoid persistent overexpression. 5-methoxyindole metabolites of L-tryptophan represent a new class of compounds that control COX-2 expression at th...
Autores principales: | Wu, Kenneth K, Cheng, Huei-Hsuan, Chang, Tzu-Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975872/ https://www.ncbi.nlm.nih.gov/pubmed/24589238 http://dx.doi.org/10.1186/1423-0127-21-17 |
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