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Nuclear location of tumor suppressor protein maspin inhibits proliferation of breast cancer cells without affecting proliferation of normal epithelial cells
BACKGROUND: Maspin, which is classified as a tumor suppressor protein, is downregulated in many types of cancer. Several studies have suggested potential anti-proliferative activity of maspin as well as sensitizing activity of maspin for therapeutic cytotoxic agents in breast cancer tissue culture a...
Autores principales: | Machowska, Magdalena, Wachowicz, Katarzyna, Sopel, Mirosław, Rzepecki, Ryszard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975902/ https://www.ncbi.nlm.nih.gov/pubmed/24581141 http://dx.doi.org/10.1186/1471-2407-14-142 |
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