Cargando…

Association of liver X receptor α (LXRα) gene polymorphism and coronary heart disease, serum lipids and glucose levels

BACKGROUND: To explore the relationship between the liver X receptor α gene (LXRα) rsl2221497 polymorphism and the susceptibility of coronary heart disease (CHD) and serum lipids and glucose levels. METHODS: The single fluorescently labeled probes technique was used to detect the genotype of rsl2221...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Yun-Fei, Zhang, Jing, Li, Zong-Xue, Miao, Jing-Li, Yin, Qiao-Xiang, Li, Jun-JIE, Zhang, Xiao-Yan, Li, Yuan-Yuan, Luo, Hui-Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975963/ https://www.ncbi.nlm.nih.gov/pubmed/24533572 http://dx.doi.org/10.1186/1476-511X-13-34

Ejemplares similares

The marine‐derived furanone reduces intracellular lipid accumulation in vitro by targeting LXRα and PPARα
por: Li, Ting, et al.
Publicado: (2020)

LXRα and LXRβ Nuclear Receptors Evolved in the Common Ancestor of Gnathostomes
por: Fonseca, Elza, et al.
Publicado: (2017)

Cholesterol efflux is LXRα isoform-dependent in human macrophages
por: Ma, A Zhi Sha, et al.
Publicado: (2014)

Expression and clinical significance of LXRα and SREBP-1c in placentas of preeclampsia
por: Jianhua, Li, et al.
Publicado: (2016)

Establishment of a monoclonal antibody for human LXRα: Detection of LXRα protein expression in human macrophages
por: Watanabe, Yuichiro, et al.
Publicado: (2003)

The Liver X Receptor Is Upregulated in Monocyte-Derived Macrophages and Modulates Inflammatory Cytokines Based on LXRα Polymorphism
por: Kim, Hyoun-Ah, et al.
Publicado: (2019)

Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure
por: Mansuy-Aubert, Virginie, et al.
Publicado: (2015)

Compound K Attenuates the Development of Atherosclerosis in ApoE(−/−) Mice via LXRα Activation
por: Zhou, Li, et al.
Publicado: (2016)

LXRα Regulates Hepatic ChREBPα Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice
por: Fan, Qiong, et al.
Publicado: (2017)

Foam Cell Specific LXRα Ligand
por: Feldmann, Radmila, et al.
Publicado: (2013)

Chronic Activation of LXRα Sensitizes Mice to Hepatocellular Carcinoma
por: Xie, Yang, et al.
Publicado: (2022)

Identfication of Potent LXRβ-Selective Agonists without LXRα Activation by In Silico Approaches
por: Chen, Meimei, et al.
Publicado: (2018)

Restoration of lipid homeostasis between TG and PE by the LXRα-ATGL/EPT1 axis ameliorates hepatosteatosis
por: Chen, Yulian, et al.
Publicado: (2023)

Inhibition of LXRα/SREBP-1c-Mediated Hepatic Steatosis by Jiang-Zhi Granule
por: Wang, Miao, et al.
Publicado: (2013)

The effect of genistein on lipid levels and LDLR, LXRα and ABCG1 expression in postmenopausal women with hyperlipidemia
por: Zhang, Tao, et al.
Publicado: (2019)

Sex-Related Differences of Lipid Metabolism Induced by Triptolide: The Possible Role of the LXRα/SREBP-1 Signaling Pathway
por: Jiang, Zhenzhou, et al.
Publicado: (2016)

Regulation of type 1 iodothyronine deiodinase by LXRα
por: Sakane, Yoriko, et al.
Publicado: (2017)

miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages
por: Vinod, Manjula, et al.
Publicado: (2014)

Identification and characterization of alternative splicing variants of buffalo LXRα expressed in mammary gland
por: Fan, Xinyang, et al.
Publicado: (2022)

Shen-Hong-Tong-Luo Formula Attenuates Macrophage Inflammation and Lipid Accumulation through the Activation of the PPAR-γ/LXR-α/ABCA1 Pathway
por: Zhang, Zepeng, et al.
Publicado: (2020)

The Nuclear Receptor LXRα controls the functional specialization of splenic macrophages
por: A-Gonzalez, Noelia, et al.
Publicado: (2013)

Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization
por: Cannon, Megan V, et al.
Publicado: (2015)

A novel dammarane triterpenoid alleviates atherosclerosis by activating the LXRα pathway
por: Huang, Yan, et al.
Publicado: (2023)

Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation
por: Zhou, Enchen, et al.
Publicado: (2023)

Role of Intestinal LXRα in Regulating Post-prandial Lipid Excursion and Diet-Induced Hypercholesterolemia and Hepatic Lipid Accumulation
por: Benítez-Santana, Tibiábin, et al.
Publicado: (2017)

Knockdown of LXRα Inhibits Goat Intramuscular Preadipocyte Differentiation
por: Xiong, Yan, et al.
Publicado: (2018)

2290: Control of atherosclerosis regression by LXRα S198 phosphorylation
por: Shrestha, Elina, et al.
Publicado: (2018)

Transcriptional Regulation of Human and Rat Hepatic Lipid Metabolism by the Grapefruit Flavonoid Naringenin: Role of PPARα, PPARγ and LXRα
por: Goldwasser, Jonathan, et al.
Publicado: (2010)

Synthesis and Biological Evaluation of Ginsenoside Compound K Derivatives as a Novel Class of LXRα Activator
por: Huang, Yan, et al.
Publicado: (2017)

Effects of A 4-Week Aerobic Exercise on Lipid Profile and Expression of LXRα in Rat Liver
por: Kazeminasab, Fatemeh, et al.
Publicado: (2017)

EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality
por: Chen, Tingting, et al.
Publicado: (2020)

Association study of angiotensin converting enzyme gene polymorphism with elderly diabetic hypertension and lipids levels
por: Zhou, Yun-Fei, et al.
Publicado: (2013)

Endoplasmic Reticulum Stress Affects Cholesterol Homeostasis by Inhibiting LXRα Expression in Hepatocytes and Macrophages
por: Wang, Tian, et al.
Publicado: (2020)

Sexual Dimorphism in Circadian Physiology Is Altered in LXRα Deficient Mice
por: Feillet, Céline, et al.
Publicado: (2016)

Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease
por: Becares, Natalia, et al.
Publicado: (2019)

LXRα Regulates oxLDL-Induced Trained Immunity in Macrophages
por: Findeisen, Hannes M., et al.
Publicado: (2022)

RNA binding Motif protein-38 regulates myocardial hypertrophy in LXR-α-dependent lipogenesis pathway
por: Li, Yao, et al.
Publicado: (2021)

Anthocyanins inhibit high-glucose-induced cholesterol accumulation and inflammation by activating LXRα pathway in HK-2 cells
por: Du, Chunyang, et al.
Publicado: (2015)

Simvastatin promotes NPC1‐mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL‐loaded macrophages
por: Xu, Xiaoyang, et al.
Publicado: (2016)

Antihyperglycemic mechanism of metformin occurs via the AMPK/LXRα/POMC pathway
por: Cho, Kumsun, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_qg8idtcv4lm2mr425k0h5rq2gp