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Protective effect of a sesamin derivative, 3-bis (3-methoxybenzyl) butane-1, 4-diol on ischemic and hypoxic neuronal injury

BACKGROUND: Stroke is one of the leading causes of neuronal death. Sesamin is known for neuroprotection by its antioxidant and anti-inflammatory properties but it lacks blood–brain barrier (BBB) activity. A panel of sesamin derivatives was screened and 3-bis (3-methoxybenzyl) butane-1,4-diol (BBD) w...

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Detalles Bibliográficos
Autores principales: Hou, Chien-Wei, Chen, Yi-Ling, Chuang, Shih-Hsien, Wang, Jen-Shu, Jeng, Kee-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975964/
https://www.ncbi.nlm.nih.gov/pubmed/24548760
http://dx.doi.org/10.1186/1423-0127-21-15