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Dry eye management in a Sjögren’s syndrome mouse model by inhibition of p38-MAPK pathway

BACKGROUND: To investigate the therapeutic effect of p38-MAPK inhibitor, SB203580, on dry eye in a mouse model of Sjögren’s syndrome (MRL/lpr mice). METHODS: 18 female BALB/c mice and 44 female MRL/lpr mice were included. Mice were randomly assigned to the control or treatment group. The expression...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoyun, Zou, Jun, He, Linping, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976089/
https://www.ncbi.nlm.nih.gov/pubmed/24443980
http://dx.doi.org/10.1186/1746-1596-9-5

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