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Quercetin regulates the sestrin 2-AMPK-p38 MAPK signaling pathway and induces apoptosis by increasing the generation of intracellular ROS in a p53-independent manner

The induction of apoptosis in cancer cells is a therapeutic strategy for the treatment of cancer. In the present study, we investigated the regulatory mechanisms responsible for quercetin-induced apoptosis, mamely the increased expression of sestrin 2 and the activation of the 5′ AMP-activated prote...

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Detalles Bibliográficos
Autores principales:	KIM, GUEN TAE, LEE, SE HEE, KIM, JONG IL, KIM, YOUNG MIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976123/ https://www.ncbi.nlm.nih.gov/pubmed/24535669 http://dx.doi.org/10.3892/ijmm.2014.1658

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