Cargando…
Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue
Mitochondrial DNA (mtDNA) contains unmethylated CpG motifs that exhibit immune stimulatory capacities. The aim of this study was to investigate whether mtDNA activates the Toll-like receptor 9 (TLR9)/nuclear factor-κB (NF-κB) pathway, thereby contributing to post-traumatic systemic inflammatory resp...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976143/ https://www.ncbi.nlm.nih.gov/pubmed/24535292 http://dx.doi.org/10.3892/ijmm.2014.1650 |
Search Result 1