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Complete endocardial cushion defects in pregnancy: a case report

INTRODUCTION: Complete endocardial cushion defect is a congenital heart disease characterized by a variable deficiency of the atrioventricular area in the developing heart. The mortality rate for an unrepaired endocardial cushion defect in pregnancy and the postpartum period is high. CASE PRESENTATI...

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Autores principales: Chen, Xiangjuan, Xiao, Biru, Yang, Weiyu, Chen, Yunqin, Zhang, Wenmiao, Zhu, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976158/
https://www.ncbi.nlm.nih.gov/pubmed/24607268
http://dx.doi.org/10.1186/1752-1947-8-91
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author Chen, Xiangjuan
Xiao, Biru
Yang, Weiyu
Chen, Yunqin
Zhang, Wenmiao
Zhu, Haiyan
author_facet Chen, Xiangjuan
Xiao, Biru
Yang, Weiyu
Chen, Yunqin
Zhang, Wenmiao
Zhu, Haiyan
author_sort Chen, Xiangjuan
collection PubMed
description INTRODUCTION: Complete endocardial cushion defect is a congenital heart disease characterized by a variable deficiency of the atrioventricular area in the developing heart. The mortality rate for an unrepaired endocardial cushion defect in pregnancy and the postpartum period is high. CASE PRESENTATION: We present a rare case of a pregnant woman with complete endocardial cushion defect. A 20-year-old Chinese woman with unrepaired complete endocardial cushion defect delivered a premature male baby at 33 weeks and six days of pregnancy in our hospital. The baby had a normal human karyotype and a birth defect of hypospadias deformity. Our patient died from heart failure 10 minutes after delivery. She had severe pulmonary hypertension and suspected trisomy 21. CONCLUSION: Our experience further emphasizes the necessity of prenatal screening for congenital heart defects and of prompt surgical correction for endocardial cushion defects during infancy. Mortality for endocardial cushion defect during pregnancy and the postpartum period is high and women with complete endocardial cushion defect should avoid pregnancy, especially those women who cannot intellectually judge their risks.
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spelling pubmed-39761582014-04-05 Complete endocardial cushion defects in pregnancy: a case report Chen, Xiangjuan Xiao, Biru Yang, Weiyu Chen, Yunqin Zhang, Wenmiao Zhu, Haiyan J Med Case Rep Case Report INTRODUCTION: Complete endocardial cushion defect is a congenital heart disease characterized by a variable deficiency of the atrioventricular area in the developing heart. The mortality rate for an unrepaired endocardial cushion defect in pregnancy and the postpartum period is high. CASE PRESENTATION: We present a rare case of a pregnant woman with complete endocardial cushion defect. A 20-year-old Chinese woman with unrepaired complete endocardial cushion defect delivered a premature male baby at 33 weeks and six days of pregnancy in our hospital. The baby had a normal human karyotype and a birth defect of hypospadias deformity. Our patient died from heart failure 10 minutes after delivery. She had severe pulmonary hypertension and suspected trisomy 21. CONCLUSION: Our experience further emphasizes the necessity of prenatal screening for congenital heart defects and of prompt surgical correction for endocardial cushion defects during infancy. Mortality for endocardial cushion defect during pregnancy and the postpartum period is high and women with complete endocardial cushion defect should avoid pregnancy, especially those women who cannot intellectually judge their risks. BioMed Central 2014-03-10 /pmc/articles/PMC3976158/ /pubmed/24607268 http://dx.doi.org/10.1186/1752-1947-8-91 Text en Copyright © 2014 Chen et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Chen, Xiangjuan
Xiao, Biru
Yang, Weiyu
Chen, Yunqin
Zhang, Wenmiao
Zhu, Haiyan
Complete endocardial cushion defects in pregnancy: a case report
title Complete endocardial cushion defects in pregnancy: a case report
title_full Complete endocardial cushion defects in pregnancy: a case report
title_fullStr Complete endocardial cushion defects in pregnancy: a case report
title_full_unstemmed Complete endocardial cushion defects in pregnancy: a case report
title_short Complete endocardial cushion defects in pregnancy: a case report
title_sort complete endocardial cushion defects in pregnancy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976158/
https://www.ncbi.nlm.nih.gov/pubmed/24607268
http://dx.doi.org/10.1186/1752-1947-8-91
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