Nuclear Translocation and Regulation of Intranuclear Distribution of Cytoplasmic Poly(A)-Binding Protein Are Distinct Processes Mediated by Two Epstein Barr Virus Proteins

Many viruses target cytoplasmic polyA binding protein (PABPC) to effect widespread inhibition of host gene expression, a process termed viral host-shutoff (vhs). During lytic replication of Epstein Barr Virus (EBV) we observed that PABPC was efficiently translocated from the cytoplasm to the nucleus...

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Detalles Bibliográficos
Autores principales: Park, Richard, El-Guindy, Ayman, Heston, Lee, Lin, Su-Fang, Yu, Kuan-Ping, Nagy, Mate, Borah, Sumit, Delecluse, Henri-Jacques, Steitz, Joan, Miller, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976295/
https://www.ncbi.nlm.nih.gov/pubmed/24705134
http://dx.doi.org/10.1371/journal.pone.0092593

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