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HIV-1 Nef Impairs Key Functional Activities in Human Macrophages through CD36 Downregulation

Monocytes and macrophages utilize the class A and B scavenger receptors to recognize and perform phagocytosis of invading microbes before a pathogen-specific immune response is generated. HIV-1 Nef protein affects the innate immune system impairing oxidative burst response and phagocytic capacity of...

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Detalles Bibliográficos
Autores principales:	Olivetta, Eleonora, Tirelli, Valentina, Chiozzini, Chiara, Scazzocchio, Beatrice, Romano, Ignazio, Arenaccio, Claudia, Sanchez, Massimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976297/ https://www.ncbi.nlm.nih.gov/pubmed/24705461 http://dx.doi.org/10.1371/journal.pone.0093699

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