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Metformin enhances tamoxifen-mediated tumor growth inhibition in ER-positive breast carcinoma

BACKGROUND: Tamoxifen, an endocrine therapy drug used to treat breast cancer, is designed to interrupt estrogen signaling by blocking the estrogen receptor (ER). However, many ER-positive patients are low reactive or resistant to tamoxifen. Metformin is a widely used anti-diabetic drug with notewort...

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Detalles Bibliográficos
Autores principales:	Ma, Ji, Guo, Yan, Chen, Suning, Zhong, Cuiping, Xue, Yan, Zhang, Yuan, Lai, Xiaofeng, Wei, Yifang, Yu, Shentong, Zhang, Jian, Liu, Wenchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976359/ https://www.ncbi.nlm.nih.gov/pubmed/24612549 http://dx.doi.org/10.1186/1471-2407-14-172

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