Downregulated GABA and BDNF-TrkB Pathway in Chronic Cyclothiazide Seizure Model

Cyclothiazide (CTZ) has been reported to simultaneously enhance glutamate receptor excitation and inhibit GABAA receptor inhibition, and in turn it evokes epileptiform activities in hippocampal neurons. It has also been shown to acutely induce epileptic seizure behavior in freely moving rats. Howeve...

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Detalles Bibliográficos
Autores principales: Kong, Shuzhen, Cheng, Zhihua, Liu, Jianhui, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976828/
https://www.ncbi.nlm.nih.gov/pubmed/24757570
http://dx.doi.org/10.1155/2014/310146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976828/
https://www.ncbi.nlm.nih.gov/pubmed/24757570
http://dx.doi.org/10.1155/2014/310146

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