Cargando…

Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers

The Genetics Core of the Alzheimer’s Disease Neuroimaging Initiative (ADNI), formally established in 2009, aims to provide resources and facilitate research related to genetic predictors of multidimensional Alzheimer’s disease (AD)-related phenotypes. Here, we provide a systematic review of genetic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Li, Thompson, Paul M., Potkin, Steven G., Bertram, Lars, Farrer, Lindsay A., Foroud, Tatiana M., Green, Robert C., Hu, Xiaolan, Huentelman, Matthew J., Kim, Sungeun, Kauwe, John S. K., Li, Qingqin, Liu, Enchi, Macciardi, Fabio, Moore, Jason H., Munsie, Leanne, Nho, Kwangsik, Ramanan, Vijay K., Risacher, Shannon L., Stone, David J., Swaminathan, Shanker, Toga, Arthur W., Weiner, Michael W., Saykin, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2013
Materias:	SI: Genetic Neuroimaging in Aging and Age-Related Diseases
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976843/ https://www.ncbi.nlm.nih.gov/pubmed/24092460 http://dx.doi.org/10.1007/s11682-013-9262-z

Ejemplares similares

Head injury is associated with tau deposition on PET in MCI and AD patients
por: Risacher, Shannon L., et al.
Publicado: (2021)

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
por: Thompson, Paul M., et al.
Publicado: (2014)

The effect of the top 20 Alzheimer disease risk genes on gray-matter density and FDG PET brain metabolism
por: Stage, Eddie, et al.
Publicado: (2016)

An interpretable Alzheimer’s disease oligogenic risk score informed by neuroimaging biomarkers improves risk prediction and stratification
por: Suh, Erica H., et al.
Publicado: (2023)

Memory concerns in the early Alzheimer's disease prodrome: Regional association with tau deposition
por: Swinford, Cecily G., et al.
Publicado: (2018)

Arrhythmia and other modifiable risk factors in incident dementia and MCI among elderly individuals with low educational levels in Taiwan
por: Huang, Yen-Chang, et al.
Publicado: (2022)

Added value of amyloid PET in individualized risk predictions for MCI patients
por: van Maurik, Ingrid S., et al.
Publicado: (2019)

The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI)
por: Risacher, Shannon L., et al.
Publicado: (2013)

Aging Leads to Increased Monocytes and Macrophages With Altered CSF-1 Receptor Expression and Earlier Tumor-Associated Macrophage Expansion in Murine Mesothelioma
por: Duong, Lelinh, et al.
Publicado: (2022)

Understanding human aging and the fundamental cell signaling link in age-related diseases: the middle-aging hypovascularity hypoxia hypothesis
por: Phua, Teow J.
Publicado: (2023)

Age-Related Intestinal Dysbiosis and Enrichment of Gut-specific Bacteria in the Lung Are Associated With Increased Susceptibility to Streptococcus pneumoniae Infection in Mice
por: McMahan, Rachel H., et al.
Publicado: (2022)

Impact of impaired cerebral blood flow autoregulation on cognitive impairment
por: Wang, Shaoxun, et al.
Publicado: (2022)

NAD-Linked Metabolism and Intervention in Short Telomere Syndromes and Murine Models of Telomere Dysfunction
por: Stock, Amanda J, et al.
Publicado: (2021)

Manipulating the exposome to enable better ageing
por: Shiels, Paul G., et al.
Publicado: (2021)

Younger and Older Adults’ Cognitive and Physical Functioning in a Virtual Reality Age Manipulation
por: Vahle, Nils M., et al.
Publicado: (2022)

Interaction between age and fatigue on antagonist muscle coactivation during an acute post-fatigue recovery phase
por: Harper, Sara A., et al.
Publicado: (2022)

The acceptability of homebased exercise snacking and Tai-chi snacking amongst high and low function UK and Taiwanese older adults
por: Liang, Ian Ju, et al.
Publicado: (2023)

Using nuclear envelope mutations to explore age-related skeletal muscle weakness
por: Battey, Edmund, et al.
Publicado: (2020)

An optimized mouse parabiosis protocol for investigation of aging and rejuvenative mechanisms
por: Rodriguez, Sonia L., et al.
Publicado: (2022)

Patterns of Self-Care Behaviors and Their Influence on Maintaining Independence: The National Health and Aging Trends Study
por: Mielenz, Thelma J., et al.
Publicado: (2021)

Pathobiology of the Klotho Antiaging Protein and Therapeutic Considerations
por: Prud’homme, Gérald J., et al.
Publicado: (2022)

Does the trained immune system play an important role in the extreme longevity that is seen in the Sardinian blue zone?
por: Soloski, Mark J., et al.
Publicado: (2022)

G-quadruplexes and associated proteins in aging and Alzheimer’s disease
por: Vijay Kumar, M. J., et al.
Publicado: (2023)

Editorial: Age as an effect modifier of nutrition and health
por: Tanprasertsuk, Jirayu, et al.
Publicado: (2023)

Pathogenic tau decreases nuclear tension in cultured neurons
por: Sohn, Claira, et al.
Publicado: (2023)

Membrane interaction and disulphide-bridge formation in the unconventional secretion of Tau
por: Hellén, Marianna, et al.
Publicado: (2021)

Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood–brain barrier
por: Kopel, Jonathan J., et al.
Publicado: (2021)

Regucalcin ameliorates doxorubicin-induced cytotoxicity in Cos-7 kidney cells and translocates from the nucleus to the mitochondria
por: Mohammed, Noor A., et al.
Publicado: (2022)

Lysosomes in T Cell Immunity and Aging
por: Jin, Jun, et al.
Publicado: (2021)

Considerations Regarding Public Use of Longevity Interventions
por: Liu, Yasmine J., et al.
Publicado: (2022)

Markers of aging: Unsupervised integrated analyses of the human plasma proteome
por: Coenen, L., et al.
Publicado: (2023)

Components of navigation ability and their predictors in a community-dwelling sample of older adults
por: Prevratil, Michael J., et al.
Publicado: (2023)

White matter changes in empirically derived incident MCI subtypes in the Mayo Clinic Study of Aging
por: Machulda, Mary M., et al.
Publicado: (2021)

T-Cell Aging-Associated Phenotypes in Autoimmune Disease
por: Zhao, Tuantuan V., et al.
Publicado: (2022)

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study
por: Ramanan, Vijay K., et al.
Publicado: (2013)

Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence
por: Barros, Paula R., et al.
Publicado: (2021)

Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review
por: Knufinke, Marie, et al.
Publicado: (2023)

Trends across 20 years in multiple indicators of functioning among older adults in the Netherlands
por: Timmermans, Erik J, et al.
Publicado: (2019)

Diminished Pneumococcal-Specific CD4(+) T-Cell Response is Associated With Increased Regulatory T Cells at Older Age
por: He, Samantha W. J., et al.
Publicado: (2021)

Mediterranean diet score is associated with greater allocentric processing in the EPAD LCS cohort: A comparative analysis by biogeographical region
por: Gregory, Sarah, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ad5ir850hutgvqjqpp0paoiiur