Peptidases from Latex of Carica candamarcensis Upregulate COX-2 and IL-1 mRNA Transcripts against Salmonella enterica ser. Typhimurium-Mediated Inflammation

The immunomodulatory properties of a mixture of cysteine peptidases (P1G10) obtained from the fruit lattice of Carica candamarcensis were investigated. P1G10 was obtained from fresh latex samples by chromatography in a Sephadex column and initially administered to Swiss mice (n = 5; 1 or 10 mg/kg) v...

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Detalles Bibliográficos
Autores principales: Ralph, Maria Taciana, Silva, Ayrles Fernanda Brandão, da Silva, Dayane Laíse, do Nascimento, Danielle Cristina Oliveira, da Silva, Diogo Manoel Farias, Gomes-Filho, Manoel A., Souza, Paulo Roberto Eleutério, Evêncio-Neto, Joaquim, Ramos, Márcio Viana, Salas, Carlos Edmundo, Lima-Filho, José Vitor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976864/
https://www.ncbi.nlm.nih.gov/pubmed/24757289
http://dx.doi.org/10.1155/2014/819731

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