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Erectile Dysfunction in the Elderly: An Old Widespread Issue with Novel Treatment Perspectives

Erectile dysfunction (ED) is one of the most common chronic diseases affecting men and its prevalence increases with aging. It is also the most frequently diagnosed sexual dysfunction in the older male population. A number of different diseases potentially worsening sexual function may occur in elde...

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Autores principales: Gareri, Pietro, Castagna, Alberto, Francomano, Davide, Cerminara, Gregorio, De Fazio, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976909/
https://www.ncbi.nlm.nih.gov/pubmed/24744785
http://dx.doi.org/10.1155/2014/878670
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author Gareri, Pietro
Castagna, Alberto
Francomano, Davide
Cerminara, Gregorio
De Fazio, Pasquale
author_facet Gareri, Pietro
Castagna, Alberto
Francomano, Davide
Cerminara, Gregorio
De Fazio, Pasquale
author_sort Gareri, Pietro
collection PubMed
description Erectile dysfunction (ED) is one of the most common chronic diseases affecting men and its prevalence increases with aging. It is also the most frequently diagnosed sexual dysfunction in the older male population. A number of different diseases potentially worsening sexual function may occur in elderly people, together with polypharmacy. Related causes of ED are variable and can include arterial, neurogenic, hormonal, cavernosal, iatrogenic, and psychogenic causes. The aim of the present review was to examine the main aspects of erectile dysfunction going through epidemiology and pathophysiology and revise most of ED in elderly disabled men and in those affected with psychiatric disorders. Lastly we tried to focus on the main aspects of nonpharmacological and pharmacological treatments of ED and the recreational use in the elderly. Phosphodiesterase-5 inhibitors (PDE5-I) are commonly used for on-demand or chronic treatment of ED. It is widely known that PDE5-I have lower response rates in older men than in younger patients, but they have the advantages of ease of use and excellent safety profile, also in the elderly. The old and new PDE5-I as well as the alternative treatments for ED are extensively discussed.
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spelling pubmed-39769092014-04-17 Erectile Dysfunction in the Elderly: An Old Widespread Issue with Novel Treatment Perspectives Gareri, Pietro Castagna, Alberto Francomano, Davide Cerminara, Gregorio De Fazio, Pasquale Int J Endocrinol Review Article Erectile dysfunction (ED) is one of the most common chronic diseases affecting men and its prevalence increases with aging. It is also the most frequently diagnosed sexual dysfunction in the older male population. A number of different diseases potentially worsening sexual function may occur in elderly people, together with polypharmacy. Related causes of ED are variable and can include arterial, neurogenic, hormonal, cavernosal, iatrogenic, and psychogenic causes. The aim of the present review was to examine the main aspects of erectile dysfunction going through epidemiology and pathophysiology and revise most of ED in elderly disabled men and in those affected with psychiatric disorders. Lastly we tried to focus on the main aspects of nonpharmacological and pharmacological treatments of ED and the recreational use in the elderly. Phosphodiesterase-5 inhibitors (PDE5-I) are commonly used for on-demand or chronic treatment of ED. It is widely known that PDE5-I have lower response rates in older men than in younger patients, but they have the advantages of ease of use and excellent safety profile, also in the elderly. The old and new PDE5-I as well as the alternative treatments for ED are extensively discussed. Hindawi Publishing Corporation 2014 2014-03-17 /pmc/articles/PMC3976909/ /pubmed/24744785 http://dx.doi.org/10.1155/2014/878670 Text en Copyright © 2014 Pietro Gareri et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Gareri, Pietro
Castagna, Alberto
Francomano, Davide
Cerminara, Gregorio
De Fazio, Pasquale
Erectile Dysfunction in the Elderly: An Old Widespread Issue with Novel Treatment Perspectives
title Erectile Dysfunction in the Elderly: An Old Widespread Issue with Novel Treatment Perspectives
title_full Erectile Dysfunction in the Elderly: An Old Widespread Issue with Novel Treatment Perspectives
title_fullStr Erectile Dysfunction in the Elderly: An Old Widespread Issue with Novel Treatment Perspectives
title_full_unstemmed Erectile Dysfunction in the Elderly: An Old Widespread Issue with Novel Treatment Perspectives
title_short Erectile Dysfunction in the Elderly: An Old Widespread Issue with Novel Treatment Perspectives
title_sort erectile dysfunction in the elderly: an old widespread issue with novel treatment perspectives
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976909/
https://www.ncbi.nlm.nih.gov/pubmed/24744785
http://dx.doi.org/10.1155/2014/878670
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