Association of P2Y12 Gene Promoter DNA Methylation with the Risk of Clopidogrel Resistance in Coronary Artery Disease Patients

Background. Clopidogrel inhibits the ADP receptor P2Y12 to keep down the platelet aggregation. The goal of our study is to investigate the contribution of P2Y12 promoter DNA methylation to the risk of clopidogrel resistance (CR). Methods. The platelet functions were measured by the VerifyNow P2Y12 a...

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Detalles Bibliográficos
Autores principales: Su, Jia, Li, Xiaojing, Yu, Qinglin, Liu, Yahui, Wang, Yaqing, Song, Haojun, Cui, Hanbin, Du, Weiping, Fei, Xiaohong, Liu, Junsong, Lin, Shaoyi, Wang, Jian, Zheng, Wenyuan, Zhong, Jinyan, Zhang, Lulu, Tong, Maoqing, Xu, Jin, Chen, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976931/
https://www.ncbi.nlm.nih.gov/pubmed/24745016
http://dx.doi.org/10.1155/2014/450814

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