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Insulin triggers surface-directed trafficking of sequestered GLUT4 storage vesicles marked by Rab10

Understanding how glucose transporter isoform 4 (GLUT4) redistributes to the plasma membrane during insulin stimulation is a major goal of glucose transporter research. GLUT4 molecules normally reside in numerous intracellular compartments, including specialized storage vesicles and early/recycling...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Lippincott-Schwartz, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976978/
https://www.ncbi.nlm.nih.gov/pubmed/24030635
http://dx.doi.org/10.4161/sgtp.26471