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Study on the Effect of Solution Conditions on Heat Induced-Aggregation of Human Alpha Interferon

A major problem in the formulation of therapeutic proteins is the irreversible protein aggregation. Recombinant human interferon alpha2b (rhIFNα2b) has poor stability and undergoes physical degradation. The aim of this study was to investigate the effect of solution conditions on the heat-induced ag...

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Detalles Bibliográficos
Autores principales:	Salmannejad, Faranak, Nafissi-Varcheh, Nastaran, Shafaati, Alireza, Aboofazeli, Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977050/ https://www.ncbi.nlm.nih.gov/pubmed/24711826

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