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Microevolution During Serial Mouse Passage Demonstrates FRE3 as a Virulence Adaptation Gene in Cryptococcus neoformans

Passage in mice of opportunistic pathogens such as Cryptococcus neoformans is known to increase virulence, but little is known about the molecular mechanisms involved in virulence adaptation. Serial mouse passage of nine environmental strains of serotype A C. neoformans identified two highly adapted...

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Detalles Bibliográficos
Autores principales:	Hu, Guowu, Chen, Shu Hui, Qiu, Jin, Bennett, John E., Myers, Timothy G., Williamson, Peter R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977352/ https://www.ncbi.nlm.nih.gov/pubmed/24692633 http://dx.doi.org/10.1128/mBio.00941-14

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