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Common Bile Duct Dilatations in Asymptomatic Neonates: Incidence and Prognosis

Background. This retrospective study reviewed 213 asymptomatic neonates with common bile duct (CBD) dilatations diagnosed via ultrasound to evaluate their incidence and outcomes. Materials and Methods. From August 2001 to July 2010, 18,230 abdominal ultrasound scans were performed as newborn screeni...

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Autores principales: Lin, Shun-Feng, Lee, Hung-Chang, Yeung, Chun-Yan, Jiang, Chuen-Bin, Chan, Wai-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977498/
https://www.ncbi.nlm.nih.gov/pubmed/24772168
http://dx.doi.org/10.1155/2014/392562
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author Lin, Shun-Feng
Lee, Hung-Chang
Yeung, Chun-Yan
Jiang, Chuen-Bin
Chan, Wai-Tao
author_facet Lin, Shun-Feng
Lee, Hung-Chang
Yeung, Chun-Yan
Jiang, Chuen-Bin
Chan, Wai-Tao
author_sort Lin, Shun-Feng
collection PubMed
description Background. This retrospective study reviewed 213 asymptomatic neonates with common bile duct (CBD) dilatations diagnosed via ultrasound to evaluate their incidence and outcomes. Materials and Methods. From August 2001 to July 2010, 18,230 abdominal ultrasound scans were performed as newborn screening. There were 213 (1.17%) cases of CBD dilatation. Dilatation of neonatal CBD was defined when its diameter was ≥2 mm. The neonates' birth history, CBD size, and follow-up results were analyzed. Results. In the 213 infants, four cystic dilatations (1.88%, 4/213) that were eventually diagnosed as choledochal cysts (CC). Among 209 neonates with fusiform dilatations (size 2.0–6.7 mm), 77 had ultrasound follow-up and 87% of them resolved spontaneously which were diagnosed as transient CBD dilatation (TCBDD). Eighty percent of TCBDDs resolved within 6 months. Patients with initial CBD size ≥3 mm had significantly lower resolution rate and neonates whose mothers are older than 35 years took longer time to resolve. Conclusion. The incidence of CBD dilatation in asymptomatic neonates was 1.17%. Eighty percent of TCBDDs resolved within 6 months. Regular ultrasound follow-up every 6 months may be appropriate for asymptomatic neonates with fusiform CBD dilatations to ensure resolution or progression.
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spelling pubmed-39774982014-04-27 Common Bile Duct Dilatations in Asymptomatic Neonates: Incidence and Prognosis Lin, Shun-Feng Lee, Hung-Chang Yeung, Chun-Yan Jiang, Chuen-Bin Chan, Wai-Tao Gastroenterol Res Pract Research Article Background. This retrospective study reviewed 213 asymptomatic neonates with common bile duct (CBD) dilatations diagnosed via ultrasound to evaluate their incidence and outcomes. Materials and Methods. From August 2001 to July 2010, 18,230 abdominal ultrasound scans were performed as newborn screening. There were 213 (1.17%) cases of CBD dilatation. Dilatation of neonatal CBD was defined when its diameter was ≥2 mm. The neonates' birth history, CBD size, and follow-up results were analyzed. Results. In the 213 infants, four cystic dilatations (1.88%, 4/213) that were eventually diagnosed as choledochal cysts (CC). Among 209 neonates with fusiform dilatations (size 2.0–6.7 mm), 77 had ultrasound follow-up and 87% of them resolved spontaneously which were diagnosed as transient CBD dilatation (TCBDD). Eighty percent of TCBDDs resolved within 6 months. Patients with initial CBD size ≥3 mm had significantly lower resolution rate and neonates whose mothers are older than 35 years took longer time to resolve. Conclusion. The incidence of CBD dilatation in asymptomatic neonates was 1.17%. Eighty percent of TCBDDs resolved within 6 months. Regular ultrasound follow-up every 6 months may be appropriate for asymptomatic neonates with fusiform CBD dilatations to ensure resolution or progression. Hindawi Publishing Corporation 2014 2014-03-19 /pmc/articles/PMC3977498/ /pubmed/24772168 http://dx.doi.org/10.1155/2014/392562 Text en Copyright © 2014 Shun-Feng Lin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lin, Shun-Feng
Lee, Hung-Chang
Yeung, Chun-Yan
Jiang, Chuen-Bin
Chan, Wai-Tao
Common Bile Duct Dilatations in Asymptomatic Neonates: Incidence and Prognosis
title Common Bile Duct Dilatations in Asymptomatic Neonates: Incidence and Prognosis
title_full Common Bile Duct Dilatations in Asymptomatic Neonates: Incidence and Prognosis
title_fullStr Common Bile Duct Dilatations in Asymptomatic Neonates: Incidence and Prognosis
title_full_unstemmed Common Bile Duct Dilatations in Asymptomatic Neonates: Incidence and Prognosis
title_short Common Bile Duct Dilatations in Asymptomatic Neonates: Incidence and Prognosis
title_sort common bile duct dilatations in asymptomatic neonates: incidence and prognosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977498/
https://www.ncbi.nlm.nih.gov/pubmed/24772168
http://dx.doi.org/10.1155/2014/392562
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