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Catechol-O-methyltransferase (COMT) Genotype Affects Age-Related Changes in Plasticity in Working Memory: A Pilot Study

Objectives. Recent work suggests that a genetic variation associated with increased dopamine metabolism in the prefrontal cortex (catechol-O-methyltransferase Val158Met; COMT) amplifies age-related changes in working memory performance. Research on younger adults indicates that the influence of dopa...

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Detalles Bibliográficos
Autores principales: Heinzel, Stephan, Riemer, Thomas G., Schulte, Stefanie, Onken, Johanna, Heinz, Andreas, Rapp, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977538/
https://www.ncbi.nlm.nih.gov/pubmed/24772423
http://dx.doi.org/10.1155/2014/414351