Effects of three Commercial Mouth Rinses on the Cultured Fibroblasts: An in Vitro Study

Statement of Problems: An ideal antimicrobial agent should have minimal cytotoxic effect to host cells. Purpose: The aim of this study was to determine the cytotoxic effect of three commercial mouthwashes (Chlorhexidine, Persica and Irsha) on the cultured fibroblasts. Material and Methods: For deter...

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Detalles Bibliográficos
Autores principales: Ghabanchi, J, Moattari, A, Darafshi, R, Andisheh Tadbir, A, Khorshidi, H, Shakib, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977549/
https://www.ncbi.nlm.nih.gov/pubmed/24724121
Descripción
Sumario:Statement of Problems: An ideal antimicrobial agent should have minimal cytotoxic effect to host cells. Purpose: The aim of this study was to determine the cytotoxic effect of three commercial mouthwashes (Chlorhexidine, Persica and Irsha) on the cultured fibroblasts. Material and Methods: For determining the cytotoxic effect of Irsha, Chlorhexidine and Persica, uninfected cells were grown in the absence and presence of various concentration (2,4,8,16,32,64,128) of these mouth washes for 1, 2, 3 and 4 days. Results: In this study, three mouth washes show cytotoxic effect on the cultured cells, at commercially available concentration and even diluted and Irsha was found to be the most toxic one. Cytotoxicity of three mouthwashes was reduced with decreasing concentration.

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