Effects of three Commercial Mouth Rinses on the Cultured Fibroblasts: An in Vitro Study

Statement of Problems: An ideal antimicrobial agent should have minimal cytotoxic effect to host cells. Purpose: The aim of this study was to determine the cytotoxic effect of three commercial mouthwashes (Chlorhexidine, Persica and Irsha) on the cultured fibroblasts. Material and Methods: For deter...

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Detalles Bibliográficos
Autores principales: Ghabanchi, J, Moattari, A, Darafshi, R, Andisheh Tadbir, A, Khorshidi, H, Shakib, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977549/
https://www.ncbi.nlm.nih.gov/pubmed/24724121
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author Ghabanchi, J
Moattari, A
Darafshi, R
Andisheh Tadbir, A
Khorshidi, H
Shakib, M
author_facet Ghabanchi, J
Moattari, A
Darafshi, R
Andisheh Tadbir, A
Khorshidi, H
Shakib, M
author_sort Ghabanchi, J
collection PubMed
description Statement of Problems: An ideal antimicrobial agent should have minimal cytotoxic effect to host cells. Purpose: The aim of this study was to determine the cytotoxic effect of three commercial mouthwashes (Chlorhexidine, Persica and Irsha) on the cultured fibroblasts. Material and Methods: For determining the cytotoxic effect of Irsha, Chlorhexidine and Persica, uninfected cells were grown in the absence and presence of various concentration (2,4,8,16,32,64,128) of these mouth washes for 1, 2, 3 and 4 days. Results: In this study, three mouth washes show cytotoxic effect on the cultured cells, at commercially available concentration and even diluted and Irsha was found to be the most toxic one. Cytotoxicity of three mouthwashes was reduced with decreasing concentration.
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spelling pubmed-39775492014-04-10 Effects of three Commercial Mouth Rinses on the Cultured Fibroblasts: An in Vitro Study Ghabanchi, J Moattari, A Darafshi, R Andisheh Tadbir, A Khorshidi, H Shakib, M J Dent (Shiraz) Original Article Statement of Problems: An ideal antimicrobial agent should have minimal cytotoxic effect to host cells. Purpose: The aim of this study was to determine the cytotoxic effect of three commercial mouthwashes (Chlorhexidine, Persica and Irsha) on the cultured fibroblasts. Material and Methods: For determining the cytotoxic effect of Irsha, Chlorhexidine and Persica, uninfected cells were grown in the absence and presence of various concentration (2,4,8,16,32,64,128) of these mouth washes for 1, 2, 3 and 4 days. Results: In this study, three mouth washes show cytotoxic effect on the cultured cells, at commercially available concentration and even diluted and Irsha was found to be the most toxic one. Cytotoxicity of three mouthwashes was reduced with decreasing concentration. Shiraz University of Medical Sciences 2013-06 /pmc/articles/PMC3977549/ /pubmed/24724121 Text en © 2013: Journal of dentistry (Shiraz, Iran) This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ghabanchi, J
Moattari, A
Darafshi, R
Andisheh Tadbir, A
Khorshidi, H
Shakib, M
Effects of three Commercial Mouth Rinses on the Cultured Fibroblasts: An in Vitro Study
title Effects of three Commercial Mouth Rinses on the Cultured Fibroblasts: An in Vitro Study
title_full Effects of three Commercial Mouth Rinses on the Cultured Fibroblasts: An in Vitro Study
title_fullStr Effects of three Commercial Mouth Rinses on the Cultured Fibroblasts: An in Vitro Study
title_full_unstemmed Effects of three Commercial Mouth Rinses on the Cultured Fibroblasts: An in Vitro Study
title_short Effects of three Commercial Mouth Rinses on the Cultured Fibroblasts: An in Vitro Study
title_sort effects of three commercial mouth rinses on the cultured fibroblasts: an in vitro study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977549/
https://www.ncbi.nlm.nih.gov/pubmed/24724121
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