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Amphipathic Polymers Enable the Study of Functional Membrane Proteins in the Gas Phase
[Image: see text] Membrane proteins are notoriously challenging to analyze using mass spectrometry (MS) because of their insolubility in aqueous solution. Current MS methods for studying intact membrane proteins involve solubilization in detergent. However, detergents can destabilize proteins, leadi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977578/ https://www.ncbi.nlm.nih.gov/pubmed/23072351 http://dx.doi.org/10.1021/ac302223s |