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Purification and Structural Study of the Voltage-Sensor Domain of the Human KCNQ1 Potassium Ion Channel

[Image: see text] KCNQ1 (also known as K(V)7.1 or K(V)LQT1) is a voltage-gated potassium channel modulated by members of the KCNE protein family. Among multiple functions, KCNQ1 plays a critical role in the cardiac action potential. This channel is also subject to inherited mutations that cause cert...

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Detalles Bibliográficos
Autores principales: Peng, Dungeng, Kim, Ji-Hun, Kroncke, Brett M., Law, Cheryl L., Xia, Yan, Droege, Kristin D., Van Horn, Wade D., Vanoye, Carlos G., Sanders, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977583/
https://www.ncbi.nlm.nih.gov/pubmed/24606221
http://dx.doi.org/10.1021/bi500102w