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Purification and Structural Study of the Voltage-Sensor Domain of the Human KCNQ1 Potassium Ion Channel
[Image: see text] KCNQ1 (also known as K(V)7.1 or K(V)LQT1) is a voltage-gated potassium channel modulated by members of the KCNE protein family. Among multiple functions, KCNQ1 plays a critical role in the cardiac action potential. This channel is also subject to inherited mutations that cause cert...
Autores principales: | Peng, Dungeng, Kim, Ji-Hun, Kroncke, Brett M., Law, Cheryl L., Xia, Yan, Droege, Kristin D., Van Horn, Wade D., Vanoye, Carlos G., Sanders, Charles R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977583/ https://www.ncbi.nlm.nih.gov/pubmed/24606221 http://dx.doi.org/10.1021/bi500102w |
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