Knockdown of the T-box transcription factor Brachyury increases sensitivity of adenoid cystic carcinoma cells to chemotherapy and radiation in vitro: Implications for a new therapeutic principle

Adenoid cystic carcinoma (AdCC) is highly metastatic and resistant to chemotherapy and radiotherapy. Recently, we reported that the T-box transcription factor Brachyury is a potential regulator of cancer stem cells (CSCs). Specifically, growth of CSCs was found to be controlled by Brachyury knockdow...

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Detalles Bibliográficos
Autores principales: KOBAYASHI, YOSUKE, SUGIURA, TSUYOSHI, IMAJYO, IKUMI, SHIMODA, MIYUKI, ISHII, KOTARO, AKIMOTO, NAONARI, YOSHIHAMA, NAOYA, MORI, YOSHIHIDE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977806/
https://www.ncbi.nlm.nih.gov/pubmed/24504414
http://dx.doi.org/10.3892/ijo.2014.2292

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