Computational Design of Binding Proteins to EGFR Domain II

We developed a process to produce novel interactions between two previously unrelated proteins. This process selects protein scaffolds and designs protein interfaces that bind to a surface patch of interest on a target protein. Scaffolds with shapes complementary to the target surface patch were scr...

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Detalles Bibliográficos
Autores principales: Choi, Yoon Sup, Yoon, Soomin, Kim, Kyung-Lock, Yoo, Jiho, Song, Parkyong, Kim, Minsoo, Shin, Young-Eun, Yang, Won Jun, Noh, Jung-eun, Cho, Hyun-soo, Kim, Sanguk, Chung, Junho, Ryu, Sung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977815/
https://www.ncbi.nlm.nih.gov/pubmed/24710267
http://dx.doi.org/10.1371/journal.pone.0092513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977815/
https://www.ncbi.nlm.nih.gov/pubmed/24710267
http://dx.doi.org/10.1371/journal.pone.0092513

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